Isaac Yakovlevich Pavlovsky, a friend of Anton Chekhov, was born in 1853 in the city of Taganrog, studied at Taganrog's Boys Gymnasium, was an activist at the Taganrog revolutionary circle and was arrested and tried at the so-called Trial of the 193. He became a political immigrant in 1878. He made his debut as journalist in Le Temps in 1880 with the story about his imprisonment En Cellule.
Isaak August Dorner was a German Lutheran church leader. He was a meditating theologian in nineteenth-century Germany who served as a professor of theology at the University of Berlin and had an international influence.
Isaak Izrailevich Brodsky was a Soviet painter whose work provided a blueprint for the art movement of socialist realism. He is known for his iconic portrayals of Lenin and idealized, carefully crafted paintings dedicated to the events of the Russian Civil War and Bolshevik Revolution.
Isaak Markovich Khalatnikov was a leading Soviet theoretical physicist who has made significant contributions to many areas of theoretical physics, including general relativity, quantum field theory, as well as the theory of quantum liquids. He is well known for his role in developing the Landau-Khalatnikov theory of superfluidity and the so-called BKL conjecture in the general theory of relativity.
Isaak Konstantinovich (Kushelevich) Kikoin, D.N., was a Soviet physicist of Lithuanian origin and an author of physics textbooks in Russian language who played an important role in the former Soviet program of nuclear weapons.
Isabel Angélica Allende Llona is a Chilean writer. Allende, whose works sometimes contain aspects of the genre magical realism, is known for novels such as The House of the Spirits and City of the Beasts, which have been commercially successful. Allende has been called "the world's most widely read Spanish-language author." In 2004, Allende was inducted into the American Academy of Arts and Letters, and in 2010, she received Chile's National Literature Prize. President Barack Obama awarded her the 2014 Presidential Medal of Freedom.